The causes of malignant tumors are the factors of reduced body immunity, and surgical treatment, chemotherapy, and radiotherapy have a certain degree of suppression of the body's immune system.
Therefore, in the comprehensive treatment measures of malignant testicular tumors, immunotherapy can still play a certain role as an auxiliary therapy.
1. Interferon (IFN)
Interferon is an immune substance released by a class of cells after being infected with virus, which is a drug protein.Its physical, chemical and biological properties are different from different species.The existing from white blood cells & alpha; -ifn (165 amino acids); -Ifn (166 amino acids) and immune & gamma; -IFN (146 amino acids).
Methods: intramuscular injection or local injection of tumor stoves.① In -muscle injection: Generally, 3 × 106IU each time, 1 to 3 days, the dose can be gradually increased to 108IU, and the total dose of visual efficacy and side effects are determined.② Injecting in the tumor: Generally 3 × 106IU each time, once or every other day, injected in the tumor and around it.
Side effects of interferon: There are fever, decreased weight, rash and injection site pain. Long -term application can be caused, but it can be recovered after stopping the drug, which can cause mild bone marrow suppression.
2. White blood cells-2 (1L-2)
1L-2 is a sugar protein composed of 133 amino acids and a molecular weight of 15,000.It is an active medium produced by activated T lymphocytes.In cellular immunity, 1L-2 has a main role.1L-2 The induction and enhancement of cytotoxic T lymphocytes (CTL), the activity of natural killing cells (NK) cells, enhancement of IFN & Gamma; Auxiliary T cell proliferation, the induction and proliferation of LAK cells, intermediary immune systemWait, show anti -tumor effects.
Method: ① In -muscle injection: 106U ~ 108U each time, once or every other day, 15 times for a course of treatment.
② Injecting in the tumor: Dose depends on the size of the lump.
③ Extract of the chest and abdominal cavity: After the chest water is exhausted, it is injected with 106U ~ 108U each time.
④ Hepatotic anemia in injection: It can be used to 108U at a time.
1L-2 increases side effects with the increase of its dose.Lightly appear fever, cold war, weakness, joint pain and decreased appetite, nausea and bloating. Generally, it can be relieved after drug or symptomatic treatment.The heavier side effects are heart edema and hypotension. Although most of them can be relieved after stopping the drug, very few patients will have life -threatening and should be paid attention to.
3. Yunzhi polysaccharide K (PS-K)
Adults take 1g each time, take it once, 3 times a day.It can be continuously taken or depends on the changes in the condition.It can prevent postoperative recurrence and enhance the anti -tumor effects of the therapy drugs.No obvious adverse reactions have been seen.
(Editor in charge: zero -degree warm)
