【Cause】
Most of them are functional, and a few are organic.The common reasons are the following aspects:
1. Psychiatric and neurological factors: If sexual psychology was traumatized in an early age, or lack of sexual knowledge in newlyweds, nervousness and anxiety, or disagreement between husband and wife, family relationships are not harmonious;The sensitivity of the penis is reduced, mental tension, and excessive ideological burden can cause impotence; brain or physical excessive strength, or bad mental stimulation, such as excessive depression, sadness, fear, etc., or indulgence, excessive sexual life, etc.Functional disorders appear impotence.
2. Neurological lesion: Hulkin-pituitary tumor or other parts of tumor, local damage to the brain, such as limited epilepsy, encephalitis, cerebral hemorrhage compression, etc., spinal cord injury, spinal cord tumor, chronic alcoholism, multiple sclerosis, pelvic cavity cavitySurgical injury can occur impotence.
3. Endocrine lesions: such as diabetes, incomplete pituitary function, testicular damage or low function, or hyperthyroidism in thyroid dysfunction, insufficient adrenal function can cause impotence.
4. Urinary genital organ lesions: such as, prostate hyperplasia, epididymitis, and varicocele, etc. can often lead to impotence.Some middle -aged and elderly patients are impotence caused by prostatitis and prostate hyperplasia;
5. Drug impact: Many drugs clinically have a inhibitory effect on sexual function, such as Liusi Ping, Pyrine, Gaoxin, Stable, Fast Urine, and Stomach Rehabilitation, etc. can cause impotence.
6. Chronic fatigue: The reason why fatigue can cause impotence is because of excessive muscle fatigue or the arousal of heart fatigue caused by overly brain, depression, tension, etc.The excitement of the emotional center of the cortex edge system, as well as the reduction of the secretion of the motor gonad hormone and the testicular of the pituitary gland and the reduction of sexual excitement.
[Male erection physiology]
Penis erection is the process of changes in the blood flow dynamic dynamic dynamic dynamic dynamic dynamic dynamic dynamic dynamic dynamic dynamic dynamic dynamics of the nerve-endocrine.After being sexually stimulated, non -adrenaline and non -choline neurons secrete neurotic media such as nitric oxide (NO).Nitrogen dioxide enters the penile sponge body smooth muscle cells, activates the ringing enzymes of glyphosate, and translates tritophosphate into a second merit-cyclic phosphate (CGMP).The increased CGMP concentration in the cells increases the smooth muscle of the sponge body, the sinus of the penis sponge expansion, and the increase in arterial blood flow.The volume of the penis sponge increased, and the white film around the penis sponge was passively extended and stretched, causing the inferior subordinate degraded veins of the drain sponge body to narrows, the intravenous return resistance increased, and the large hardness of the penis increased, causing the penis to erect.With the degradation of CGMP being degraded by the phosphate V (PDE5) in the flat muscle cells, it loses its activity and the sympathetic nerve recovery tension after ejaculation, and the penis turns into a weak state.Because the PDE5 selectivity is smooth in the penis sponge body, CGMP specific PDE5 inhibitors are currently the first oral drugs for treating erectile dysfunction.The internal injection of prostaglandin E1 penis sponge is used to treat erectile dysfunction. The mechanism of action is to increase CAMP synthesis by activating adenotide rotidase.In addition, the adrenaline nerve medium is in the media to discuss the smooth muscle cell contraction of the penile sponge body, the penile blood flow decreases, the vein flow is open, and the penis is weak.Phenolithera is an adrenaline receptor resistant agent, which is used for penile sponge injection therapy to treat erectile dysfunction.
