About 80 % comes from family's vertical communication
my country is called a great country B.According to statistics, there are nearly 100 million hepatitis B virus carriers in my country, that is, one of each 10 people.Although the number of hepatitis B in my country is large, not all of them are infected with patients.The vertical dissemination of hepatitis B virus includes maternal and infants and father and infants.
The ways of maternal and infants' vertical spread and corresponding prevention methods have deep research at home and abroad.RecentHowever, the spread of the father and baby of hepatitis B virus is only a way for hepatitis B virus to spread. It is not genetic diseases. Through effective prevention, vertical transmission between father and infants can be blocked.
What exactly is the spread of father and baby?
Men with hepatitis B can detect hepatitis B virus DNA in their sperm. The virus is stored in sperm head cytoplasm and sperm enters egg cells. Although his mother has no hepatitis, this fertilized egg isIt is also continuously proliferating, making this seed a patient with hepatitis B or virus carriers. Therefore, the spread of this hepatitis B virus is called father and baby transmission.
The spread of father and bodies is different from the mother and baby spread. Some studies have shown that the father of hepatitis B virus infection has been carried by the hepatitis B virus DNA fragment. This DNA fragment can exist in the cytoplasm of the sperm head.Continue to replicate in sub -cell cells, childblag cell infections occur, causing hepatitis B father and infants.In addition, even if there is no hepatitis B virus infection when fertilization, as long as the couple live together during pregnancy, pregnant women have not been out of the danger of being infected by hepatitis B virus in her husband.Because the close contact of daily life, sexual life during pregnancy, etc., may cause pregnant women to be infected by hepatitis B virus, and then infected with the child-mother-infant method. This is actually a kind of indirect father and child transmission.
When the father's surface antigen and E antigen dual -positive, the chance of infection of the baby born can reach more than 80%; when the father E antibody is positive, its offspring is about 20%.After fetal infection, hepatitis B virus can become a patient with hepatitis B or with a virus, and it can also affect the normal growth and development of the fetus, which can cause low -weight children, congenital diseases or malformations, abortion, dead tires, etc.Therefore, the spread of the father and baby of hepatitis B virus has attracted enough attention.
If the spouse is healthy, and the HBV infected person is HBSAG positive, or "Little Sanyang", "Little Eryang", HBV & MDASH; DNA negative and no clinical symptoms, normal liver function, liver and spleen B best, indicating that HBV is in the HBV inThere is no copy in the body, and the infectious is extremely weak.
Because the direct parental and infants have occurred in the reproductive cell stage, the most effective way to block the spread of hepatitis B father and infants is pre -pregnancy intervention.
First, the newlywed couple must conduct hepatitis B before marriage. No matter whether men and women suffer from hepatitis B, they should be actively treated.It is best to get breeding without infection or stable condition.If the mother can successfully immune to the antibody before pregnancy, it is the best pregnancy period at this time, which can effectively protect pregnant women and newborns, which can effectively reduce the possibility of infection with hepatitis B virus.
2. The method of preventing father and infants is to vaccinate newborns in time in accordance with the planned immunization measures. Children can vaccinate the hepatitis B vaccine in their lives.There are also some beneficial methods for options: during the period of pregnancy, a hepatitis B immunoglobulin was scheduled every 4 weeks of age, which can effectively neutralize the hepatitis B virus in the blood of pregnant women. The purpose is to further strengthen the resistance of pregnant women to resist resistanceHusband's ability to infection with hepatitis B virus, while reducing the opportunity to spread hepatitis B virus-mother-baby transmission.Father (or) mothers for hepatitis B virus carrier, in addition to injection of hepatitis B vaccine in accordance with regulations, should also inject high -efficiency hepatitis B immunoglobulin within 24 hours after birth.Protection newborn.
Therefore, we remind us that the case of the basis for the infection of hepatitis B virus in only the husband and wife should strengthen the mission, so that it has a deeper understanding of the transmission of hepatitis B virus, so as to better cooperate with doctors to use reasonable methods to prevent pregnant women and child generations from exempting from generation to generation.The occurrence of hepatitis B virus infection.
(Editor in charge: Internship Liu Suqiong)
