When it comes to chromosomes, it is thought that it is related to genetic genetic, and no spermist is indeed possible to eventually produce non -sperm disease due to chromosomal abnormalities.What about the specific situation? Let's take a look at it together.
For patients with abnormal chromosomes, from the inquiry of the medical history, some patients can find that some patients have puberty delay, low intelligence, language and cognitive ability defects, and varying degrees of psychological obstacles.Physical examinations can be found that some patients are lacking in secondary sexual characteristics, short penis, and testicular.
Sex hormone testing generally shows that the LH and FSH are elevated, and the value of T (testosterone) is reduced. The diagnosis is mainly dependent on chromosomal nuclear analysis or the detection of Y chromosomal micro -deletion.Such patients generally no longer need to perform testicular pathological examinations.If some patients with test nine doctors can find that the diameter of the fine sperm tubes can be found, and the fine sperm tube wall has no spermatogenic cells and only supports cells. The base membrane is thickened or transparent.Essence
Chromosomal abnormalities, including the number of chromosomes abnormalities and the structure of chromosomes.Most of the number of chromosomal numbers increased the number of chromosomes.It is generally caused by the fact that the homologous chromosomes are not separated when the ovarian mother cell decomposition is separated. Studies believe that the elderly is one of the risk factors.
The structural abnormalities of chromosomes include the break, absence, inverted, and priced position of chromosomes.In addition, there is a micro -lack of Y chromosomal long -armed deficiency factor (AZF).The study of Y chromosome micro -lack has been paid more and more attention.Studies have found that there is a region with fertility -related factor in the long arm of male Y chromosome, called the AZF region.It is believed that there are 4 sperm in the AZF district (AZFA, AZFB, AZFC, AZFD). The sites contained in each Asian area play a different role in the development of male reproductive cells.It is manifested as less, or sperm -free, which causes infertility.
From this, it can be understood that the azoospermia is mainly related to the Y chromosomes. When it occurs, it will lead to the production of no sperm. The type of no seizure caused by different sites is also different.
(Editor in charge: Internship Zhang Yiwen)
