Many genetic diseases can cause male infertility.So which genetic diseases can cause male infertility?There are about a few:
(1) KLINEFELTER syndrome
It has many names, such as the developmental dysplasia of the sperm tube, the retrofitting degeneration of the sperm tube of the sclerosis, the congenital test dragon developmental disorders, and the primary small testisia.This symptoms perform mild before puberty, and they are often not noticed.As of adolescence, the typical symptoms are that the testicles are small and hard, and the long diameter does not exceed 2 cm, which is about one -half of the average length of normal adult men.Sleeid, delicate skin, long body hair.The beard is sparse, and about half of the feminine breasts, low sexual functions, and no fertility in adolescence.Some patients have low intelligence.Testes living tissue examination can be seen in the transparent degeneration of the sperm tubular, the base membrane is significantly thickened, the blood cells atrophy, and the disappearance is disappeared.Testeous intercocuretic fiber hyperplasia, multi -clustering of interstitial cells, and decreased intracellular droplets.Plasma testosterone content is normal or low, estrogen production increases, and the proportion of the two is imbalance.Most cases of blood and urine -promoting gonadotropin content have increased significantly, especially the rise in FSH content is the most significant.Sperm examination sperm is very small or no sperm.
(2) XX male syndrome (XXMALES)
The chromosomal type of this syndrome is 46, XX, but the internal and external genitals are male, and the second sexual symptoms of men with a slightly worse manner in the adolescence.Its clinical manifestations, pathology and endocrine examination are similar to KLINEFELTER syndrome.
