Male infertility brings great pain to patients, and there are many causes of this disease. The following genetic diseases can lead to male infertility:
Congenital testicular dysplasia
Congenital testicular development is mild before adolescence. It is often not noticed. The typical symptoms of adolescence are small and hard testicular, and the length of the diameter is not more than 2cm. It is about 1/2 of the average length of normal adult men.Half of the adolescence presents feminized breasts, low sexual function, and no fertility. Some patients have mild intelligence low, testicular living tissue examination can be seen in the transparent degeneration of sperm tubes, significant thickening of the base membrane, the atrophy of sperm cells, and even disappear.Only support cells, and the inner cavity is mostly blocked.Testeous intercocuretic fiber hyperplasia, multi -clustering of interstitial cells, and decreased intracellular droplets.Plasma testosterone content is normal or low, estrogen production increases, and the proportion of the two is imbalance.Semen checking the amount of sperm is very small or spermatic, leading to male infertility.
Xx male syndrome
The chromosomal type of XX male syndrome is 46, XX, and the internal and external genitals are male.Its clinical manifestations, pathology and endocrine examination are similar to congenital testicular dysplasia.
Testicular
The nucleus type of testis is normal male type, 46, xy, and the internal and external reproductive organs are male, congenital no testicles, so that they cannot show sexual maturity during adolescence.The second sex is naive, with short penis, presence and infertility.High -promoting gonadotropin content in blood is a typical primary single -pill dysfunction.
(Editor in charge: Internship Zhang Yiwen)
