The causes of men's infertility are complicated and multi -faceted. Some drugs used for the treatment of diseases can also cause male sperm disorders and make male infertility.
The mechanism of drugs that cause male infertility is that some drugs can directly inhibit the division of the cells of the testicular intramuscular tube.It hinders the formation of normal sperm cells; certain drugs can indirectly interfere with the testicular function through hormones to create sperm function by inhibiting the human body's brain & mdash; pituitary system.Drugs that directly suppress testicular tubular cells such as sperm tubular cells, such as nitrifuxu, dichlorohlotchloride, pneumophyte, etc., can prevent the protein synthesis of sperm cells and primary sperm cells.It has a suppressing effect on making fine function.
According to relevant information, some drugs with a hydroxytic compound structure, such as nitrogen -orbinate, and phosphates, can inhibit the creation function, and it is not easy to return to normal even if the drug is discontinued;Using can affect the essence function to varying degrees. If you use Changchun Shin -alkali, it will damage the essence function by inhibiting the synthesis of mRNA ("messenger" in the cells in the cell) and the synthesis of protein.The division of cells, primary sperm cells and sperm cells has stagnated and lost her pregnancy.However, this damage is different from the hydroxygenic compounds. The degree of damage to the cells is mild, and the testicular interlayer cells are normal. Once the medication is stopped, the function of making essence can return to normal;The normal activity of the receptor causes the sperm to become abnormal.
Drugs that affect the pituitary function, such as monocular amine oxidase inhibitors, can reduce pituitary secretion to promote gonad hormone; a large amount of steroid hormones, such as testosterone and progesterone, androgen, can also indirectly inhibit the creation function.There are many drugs that affect men's sperm function, and are closely related to the combination of drugs, the amount of usage, and the length of use.What is easy to be ignored is that a large number of aspirin and vitamin B12, vitamin E, etc. can also inhibit the creation function, and should also pay attention.
(Editor in charge: Internship Liu Suling)
