◆ Dopamine antagonist ◆
Such drugs, including anti -psychiatric drugs (also known as mental inhibitory drugs), can block the dopamine receptor that can block the center.By observing the sexual excitement of Apumorine (dopamine excitement), it can be antagonal by fluoroprine (dopamine receptor blockers in the center), and can also be antagonal by atypical dopamine receptor blockers sulfenidamineHowever, the fact that the fact that the dopamine receptor blocker that cannot be passed through the blood -brain barrier does not antagonize the fact that drugs have an effect on delay ejaculation.Dopamine antagonist shows a clear role in inhibiting ejaculation on humans or animals, including Pimitett (Anti -Psychiatric), metharoxylramine (tinentyl), sulfenidamine, fluoropylinol, and oxytocin.Antagonist, oxytocin.Other anti -psychiatric drugs that can delay ejaculation include chloropyrazine and sulidine. These two drugs can also block the receptor of adrenaline.
◆ Anti -anxiety drugs ◆
Many of them are known to treat the phenolin zitzen anti-anxiety drugs that are used for extensive anxiety and anxiety. It has the effect of inhibiting ejaculation in some men. The mechanism may be that GABA (G-aminobutyric acid) is strengthened.These drugs include Liming Ning, Laurax, and Apzolun.However, their impact on ejaculation is not as common and obvious as other drugs (such as SSRIS). The comparison research shows that less than 10%of men taking such drugs are delayed than before.
◆ Anti -depression drugs ◆
Antidepressant is a new generation of delayed ejaculation drugs, which can improve the level of 5-hydrolytic (5-HT) in the human body.These drugs include 5-HT's removal of selective inhibitors (SSRIS) Flobidin, Shequlin and Parosdine.While blocking 5-HT, these drugs also have the effect of anti-choline energy.The rise of the 5-HT level is considered one of the mechanisms to suppress ejaculation.Old three -ring antidepressants also affect ejaculation.These drugs have the characteristics of sedation, anti-choline energy and antihistamines, and also hindered the re-intake of 5-HT.
However, the obstacles of these drugs have less selectivity of the 5-HT re-intake, and their other characteristics may have a poor impact on patients' compliance.Among these drugs, chlorobylzide has a hindered effect on the re-intake of 5-HT and tormeal adrenaline.Chlorobylzide can improve the stimulating threshold of the genital site sensor, but there is no effect on the evolution of the sacrum or the arousal of the back side nerve body feel.Another three -ring antidepressant drug that suppress ejaculation is amparin forest, which has obvious anti -choline energy effects.
