Long -term medication can lead to male infertility. The following is a mechanism for infertility caused by drugs:
1. Directly inhibit the division of testicular tube cells.Such as nitrogen bearing, dichlorohlotchloride, pneumophyte and other drugs can prevent the protein synthesis of spermocytes and primary sperm cells. Even if it is used in common amount, it will also inhibit the essence function; some hydroxyl groups will be inhibited; some hydroxyl groups willDrugs with compound structures, such as phenyl -nitrate mustard, cyclopensicide, etc. can inhibit the creation of fine function, and it is not easy to return to normal even if drugs are discontinued; a large amount of steroid hormones, such as testicular ketone and progesterone, androgen, will also indirectly suppressFunctional function.
2. Many anti -cancer drugs, whether they are separate or jointly used, can affect the fineness function to varying degrees. For example, the use of Changchun new alkali will damage the essence function by inhibiting the synthesis of MRNA and the synthesis of protein, and the internal testicles in the testicles.The division of spermocytes, primary sperm cells and sperm cells stagnate.
3. Directly inhibit the division of the cells of the testicular endogenic tube, which hinders the formation of normal sperm cells; Simiidine used to treat ulcer disease can hinder the normal activity of the male hormone receptor and cause abnormal sperm;Drugs, such as monocular amine oxidase inhibitors, can secrete the pituitary glandular hormone; by inhibiting the human body's brain & mdash; pituitary system, it indirectly interferes with the function of the testicular sperm through hormones.
(Editor in charge: Internship Zhang Yiwen)
